Author

Guanghui Tian

Chinese Academy of SciencesORCID 0000-0002-7988-5715Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Assay:behavioral assay· 1 Research Focus:drug response / drug discovery· 1 Assay:electrophysiology· 1 Research Focus:host-pathogen & immune response· 1 Organism:mouse· 1 Organism:virus· 1

Frequent Co-Authors

Jingshan SheniD· 2 shared Yan ZhangiD· 2 shared Baiyang Zheng· 1 shared Chunyou MaoiD· 1 shared Dandan SheniD· 1 shared Fulai ZhouiD· 1 shared Guan Wang· 1 shared H. Eric XuiD· 1 shared

Activity by Year

2020-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

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2 shared papersNeuroscience

Jingshan ShenORCID

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2 papers

Recent·Most cited

NeurosciencebioRxivPreprintNov 9, 2026

Serotonin Reuptake Inhibition Reduces NMDAR-Associated Reward Liability Without Compromising Rapid Antidepressant Efficacy

Libiao Pan, Guan Wang, Jing Ji…·Jingshan Shen

This study shows that combining serotonin reuptake inhibition with NMDAR antagonism reduces reward-related effects while maintaining rapid antidepressant efficacy.

DOI 10.64898/2026.11.01.763059

mousebehavioral assay

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Molecular BiologySciencePeer-reviewedMay 1, 2020

Structural Basis for the Inhibition of the RNA-Dependent RNA Polymerase from SARS-CoV-2 by Remdesivir

Wanchao Yin, Chunyou Mao, Xiaodong Luan…·H. Eric Xu

This study reports the structure of SARS-CoV-2 RdRp with and without Remdesivir, showing how the drug inhibits viral RNA replication by terminating chain elongation.

1,219 citationstop 1%

virusexperimental assay

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