Author

Leighton J. Payne

University of OtagoORCID 0000-0003-2305-6827Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:bacteria (other)· 2 Research Focus:host-pathogen & immune response· 2 Organism:multiple species· 1 Assay:proteomics· 1

Frequent Co-Authors

Simon A. JacksoniD· 2 shared Aritz Roa-EguiaraiD· 1 shared David SünderhaufiD· 1 shared Freddie J. O. MartiniD· 1 shared Haidai HuiD· 1 shared Ivo Alexander HendriksiD· 1 shared Jahn R RinggeriD· 1 shared Marc ErhardtiD· 1 shared

Activity by Year

2023-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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2 shared papersMicrobiology

Simon A. JacksonORCID

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3 papers

Recent·Most cited

MicrobiologyPLoS BiologyPeer-reviewedFeb 19, 2026

CRISPR-Cas is beneficial in plasmid competition, but limited by competitor toxin-antitoxin activity when horizontally transferred

David Sünderhauf, Jahn R Ringger, Leighton J. Payne…·Stineke van Houte

This study shows that plasmid-borne CRISPR-Cas is beneficial in plasmid competition but is hindered by toxin-antitoxin systems in horizontally transferred plasmids.

5 citationstop 2%

experimental assayhost-pathogen & immune response

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MicrobiologybioRxivPreprintJan 29, 2024

New antiviral defences are genetically embedded within prokaryotic immune systems.

Leighton J. Payne, Tom C. D. Hughes, Peter C. Fineran, Simon A. Jackson

The paper identifies new antiviral defence systems in prokaryotes by analyzing genetic embedding of uncharacterized genes within known defence systems.

37 citations

bacteria (other)multiple species

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Molecular BiologybioRxivPreprintDec 18, 2023

Structure and mechanism of Zorya anti-phage defense system

Haidai Hu, Thomas C.D. Hughes, Philipp F. Popp…·Nicholas M. I. Taylor

This study reveals the structure and mechanism of the Zorya anti-phage defense system using cryo-EM and functional assays, showing how it detects phage invasion and activates defense.

13 citations

bacteria (other)proteomics

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