Author

Kai Liu

Broad InstituteORCID 0000-0002-8014-2310Unclaimed ORCID profile · follow to get notified of new preprints

Additional preprints under this name without ORCID

Kai Liu5 papers · ByteDance (China)

Biology Disciplines

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Genetic & Genomic Medicine· 1 Genetics· 1

Signature Assays, Organisms & Methods

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Research Focus:gene regulatory network inference· 2 Assay:scRNA-seq· 2 Approach:statistical model· 2 Research Focus:eQTL / molecular QTL mapping· 1 Organism:human· 1 Organism:mouse· 1 Assay:scATAC-seq· 1

Frequent Co-Authors

Daniel B. GrahamiD· 2 shared Orr AshenbergiD· 2 shared Ramnik J. XavieriD· 2 shared Aarno V. PalotieiD· 1 shared Aviv RegeviD· 1 shared Caroline B. M. PorteriD· 1 shared Chenhao LiiD· 1 shared Cristin AubiniD· 1 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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2 shared papersGenetic & Genomic Medicine

Daniel B. GrahamORCID

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2 papers

Recent·Most cited

Population-scale multiome immune cell atlas reveals complex disease drivers

Masahiro Kanai, Toni Marie Delorey, Jarno K. Honkanen, Rodosthenis S. Rodosthenous, Julianna Juvila, Shane M. Murphy, Isabella Teixeira-Soldano, Hee Seung Hwang, Juha M Karjalainen, Jussi Halonen, Georgia Panagiotaropoulou, Yuanxiang Zhang, Cristin Aubin, Eric Chen, Kosaku Nanki, , Ramnik J. Xavier

The paper uses population-scale single-nucleus ATAC-seq and RNA-seq to identify regulatory variants and their disease associations in immune cells.

medRxiv · Nov 25, 2025 · PreprintGenetic & Genomic Medicine

Prevalent cross-cell type QTL trans-regulatory genetic effects impacting innate lymphoid cells in the small intestine

Miao Xu, Kirk Gosik, Yang Zang, Orr Ashenberg, Chenhao Li, Hongjun Li, Kai Liu, Gary A. Churchill, Daniel M. Gatti, Kwangbom Choi, Vivek M. Philip, Daniel B. Graham, Kushal K. Dey, Heping Xu, Ramnik J. Xavier, Aviv Regev

The paper identifies genetic variants affecting innate lymphoid cells in the gut using single-cell RNA-seq and validates their regulatory roles across cell types.

bioRxiv · Apr 16, 2025 · PreprintGenetics