Author

Katharina Rox

German Center for Infection ResearchORCID 0000-0002-8020-1384Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 2 Organism:bacteria (other)· 1 Assay:CRISPR screen· 1 Approach:deep learning· 1 Approach:experimental assay· 1 Organism:human· 1 Approach:statistical model· 1

Frequent Co-Authors

Abdelhakim BoudriouaiD· 1 shared Alain Morejon Morales· 1 shared Alexander Kohler· 1 shared Alexandra K. KiemeriD· 1 shared Anand KrishnaniD· 1 shared Andrew FreywaldiD· 1 shared Angie Chen· 1 shared Anjali SaxenaiD· 1 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperMicrobiology

Abdelhakim BoudriouaORCID

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2 papers

Recent·Most cited

Cancer BiologyCell GenomicsPeer-reviewedMay 9, 2025

Identification of targetable vulnerabilities of PLK1-overexpressing cancers by synthetic dosage lethality

Chelsea E. Cunningham, Frederick S. Vizeacoumar, Yue Zhang…·Franco J. Vizeacoumar

The paper identifies synthetic dosage lethality targets for PLK1-overexpressing cancers using genome-wide screens and validates key hits to show their therapeutic potential.

8 citations

humanCRISPR screen

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MicrobiologyScience AdvancesPeer-reviewedApr 11, 2025

Discovery of a synthetic small molecule targeting the central regulator of Salmonella pathogenicity

Abdelhakim Boudrioua, Joe D. Joiner, Iwan Grin…·Samuel Wagner

The paper identifies a synthetic small molecule, C26, that inhibits HilD, a key regulator of Salmonella secretion systems, thereby preventing bacterial invasion of host cells.

4 citations

bacteria (other)experimental assay

𝕏 PostBluesky