Bianca Plouffe

The paper identifies a conserved hydrophobic interaction that mediates competition between GPCR transducers and regulators.

The paper identifies a BMP-dependent endocytosis pathway for GREM1 in epithelial cells, showing BMP binding is required for GREM1 uptake and antagonism of BMP signaling.

The paper shows that US28's Gq/11 signaling from the plasma membrane, not endosomes, primarily drives gene expression related to glioblastoma proliferation and inflammation.

The paper investigates how multiple triggers on an allosteric communication network influence preferential coupling of the CB2R to Gi2 over β-arrestin1, revealing insights into GPCR signaling mechanisms.

The paper shows that cell-to-cell variations in V2R subcellular localization are independent of expression levels and influenced by cell-specific environments.