Author

Joshua A. Kulas

University of VirginiaORCID 0000-0002-8055-1894Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:mouse· 3 Research Focus:cell-cell communication· 2 Research Focus:differential expression· 2 Research Focus:gene regulatory network inference· 2 Assay:bulk RNA-seq· 1 Assay:imaging· 1 Approach:statistical model· 1

Frequent Co-Authors

Heather Anne FerrisiD· 3 shared Hao WangiD· 2 shared Scott B. HanseniD· 2 shared Adriano AguzziiD· 1 shared Aminata P. CoulibalyiD· 1 shared Anton M. Schüle· 1 shared Chao WangiD· 1 shared Claire E. Peng· 1 shared

Activity by Year

2019-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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3 shared papersNeuroscience

Heather Anne FerrisORCID

Mutual co-authors in cluster

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3 papers

Recent·Most cited

NeurosciencebioRxivPreprintDec 12, 2022

Regulation of neuroinflammation by astrocyte-derived cholesterol.

Hao Wang, Joshua A. Kulas, Yang Yu…·Scott B. Hansen

This study shows that astrocyte-derived cholesterol, released via apoE, promotes neuroinflammation by enhancing inflammatory signaling in immune cells.

11 citations

mousebulk RNA-seq

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NeuroscienceProceedings of the National Academy of SciencesPeer-reviewedAug 12, 2021

Regulation of beta-amyloid production in neurons by astrocyte-derived cholesterol

Hao Wang, Joshua A. Kulas, Chao Wang…·Scott B. Hansen

The paper shows astrocyte-derived cholesterol regulates amyloid precursor protein trafficking to lipid rafts, affecting Aβ and sAPP production in neurons, and disrupting cholesterol synthesis reduces amyloid pathology in mice.

293 citationstop 1%

mouseimaging

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NeurosciencebioRxivPreprintOct 19, 2019

The neutrophil enzyme myeloperoxidase directly modulates neuronal response after subarachnoid hemorrhage, a sterile injury model

Aminata P. Coulibaly, Pınar Pezük, Paul Varghese…·J. Javier Provencio

This study shows that myeloperoxidase from neutrophils in the meninges modulates neuronal function after subarachnoid hemorrhage, leading to cognitive deficits.

1 citation

mouseexperimental assay

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