Jeroen Leijten

Xolographic printing of cell-dense engineered living matter via iodixanol-driven enhancement of type II photoinitiation

This paper demonstrates that iodixanol enhances type II photoinitiation reactivity, enabling high-cell-density Xolographic printing of functional engineered living matter.

Self-feeding living materials enabled by cell responsive glycogen nanoparticles as metabolic batteries

This paper introduces glycogen-based nutritional nanoparticles as metabolic batteries to support long-term survival of human mesenchymal stromal cells under extreme metabolic stress and enables scalable living materials.

Intracellular crowding links dimensionality to cell fate through a mechano-metabolic signalling axis

This study shows that cell culture dimensionality affects intracellular crowding, which influences cell fate through a mechano-metabolic signaling pathway, improving chondrogenic differentiation in microtissue cultures.

Covalent on-cell conjugation of biomaterials through oxidative phenolic coupling regulates stem cell fate via intracellular biophysical programming

This study uses covalent on-cell oxidative phenolic coupling to tether hydrogels to stem cells, showing it regulates cell fate through biophysical changes without relying on YAP/TAZ signaling.