Author

Timothy J. Shafer

Environmental Protection AgencyORCID 0000-0002-8069-9987Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Neuroscience· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Research Focus:drug response / drug discovery· 1 Assay:spatial transcriptomics· 1

Frequent Co-Authors

Benjamin L.L. ClaytoniD· 1 shared Erin Frances Cohn· 1 shared J A Conley· 1 shared J. Monroe· 1 shared Katie Paul FriedmaniD· 1 shared Kelly E. CarstensiD· 1 shared Kristin A. Lee· 1 shared M Mayil Vahanan· 1 shared

Activity by Year

2024-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperNeuroscience

Benjamin L.L. ClaytonORCID

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2 papers

Recent·Most cited

Development of a network formation assay for developmental neurotoxicity hazard screening using 3D human iPSC derived BrainSpheres

S. Boyd, M Mayil Vahanan, J. Monroe, J A Conley, Kelly E. Carstens, Timothy J. Shafer

The paper develops a 3D human iPSC-derived BrainSphere model on hdMEAs to screen for developmental neurotoxicity by measuring neural network activity and disruption from chemical exposures.

NeuroToxicology · Oct 15, 2025Peer-reviewedNeuroscience

Pervasive environmental chemicals impair oligodendrocyte development

Erin Frances Cohn, Benjamin L.L. Clayton, Mayur Madhavan, Kristin A. Lee, Sara G. Yacoub, Yuriy Federov, Marissa A. Scavuzzo, Katie Paul Friedman, Timothy J. Shafer, Paul J. Tesar

This study identifies two classes of environmental chemicals that impair oligodendrocyte development through distinct mechanisms and links exposure to adverse neurodevelopmental outcomes.

Nature Neuroscience · Mar 25, 2024Peer-reviewedNeuroscience