Author

Mayur Madhavan

Case Western Reserve University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Neuroscience· 2 Developmental Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1

Frequent Co-Authors

Paul J. TesariD· 3 shared Artur S. Gevorgyan· 2 shared Benjamin L.L. ClaytoniD· 2 shared Erin Frances Cohn· 2 shared Kevin Cameron AllaniD· 2 shared Marissa A. ScavuzzoiD· 2 shared Stevephen HungiD· 2 shared Adam Swayze· 1 shared

Activity by Year

2020-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

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3 shared papersNeuroscience

Paul J. TesarORCID

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Author profile →

3 papers

Recent·Most cited

Pervasive environmental chemicals impair oligodendrocyte development

Erin Frances Cohn, Benjamin L.L. Clayton, Mayur Madhavan, Kristin A. Lee, Sara G. Yacoub, Yuriy Federov, Marissa A. Scavuzzo, Katie Paul Friedman, Timothy J. Shafer, Paul J. Tesar

This study identifies two classes of environmental chemicals that impair oligodendrocyte development through distinct mechanisms and links exposure to adverse neurodevelopmental outcomes.

Nature Neuroscience · Mar 25, 2024Peer-reviewedNeuroscience

Non-Canonical Targets of HIF1a Drive Cell-Type-Specific Dysfunction

Kevin Cameron Allan, Lucille R. Hu, Marissa A. Scavuzzo, Andrew R. Morton, Artur S. Gevorgyan, Erin Frances Cohn, Benjamin L.L. Clayton, Ilya R. Bederman, Stevephen Hung, Cynthia F. Bartels, Mayur Madhavan, Paul J. Tesar

This study identifies non-canonical HIF1a targets that impair oligodendrocyte progenitor cell function and drive disease in chronic hypoxia.

Cell stem cell · Oct 21, 2020Peer-reviewedDevelopmental Biology

Therapeutic suppression of proteolipid protein rescues Pelizaeus-Merzbacher Disease in mice

Matthew S. Elitt, Lilianne Barbar, H. Elizabeth Shick, Berit E. Powers, Yuka Maeno-Hikichi, Mayur Madhavan, Kevin Cameron Allan, Baraa S. Nawash, Artur S. Gevorgyan, Stevephen Hung, Zachary Scott Nevin, Hannah E. Olsen, Midori Hitomi, Daniela Schlatzer, Hien Tran Zhao, , Paul J. Tesar

This paper shows that reducing PLP1 expression in a mouse model of PMD improves myelination, motor function, and lifespan, supporting PLP1 suppression as a therapeutic strategy.

Nature · Jul 1, 2020Peer-reviewedNeuroscience