Author

Megan R. Teh

John Radcliffe HospitalORCID 0000-0002-8095-9961Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Immunology· 2 Cell Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:human· 3 Research Focus:cell signaling & trafficking· 2 Research Focus:cell type annotation· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1 Assay:flow cytometry· 1

Frequent Co-Authors

Hal DrakesmithiD· 3 shared Giulia PironaciiD· 2 shared Huei-Wen Chuang· 2 shared Jon WadeiD· 2 shared Michalina MazurczykiD· 2 shared Philip HoldshipiD· 2 shared Robert George HiltoniD· 2 shared Alastair L. Smith· 1 shared

Activity by Year

2024-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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3 shared papersImmunology

Hal DrakesmithORCID

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3 papers

Recent·Most cited

Cell-type specific iron content regulation revealed by single-cell iron quantification

Philip Holdship, Megan R. Teh, Michalina Mazurczyk, Dana Costigan, Giulia Pironaci, Huei-Wen Chuang, Michael Bruce Zimmermann, Nicole Ursula Stoffel, Robert George Hilton, David Price, Jon Wade, Hal Drakesmith

The paper quantifies cellular iron content in immune cells using sc-ICP-MS and finds cell-type and activation state-specific iron regulation.

bioRxiv · Jun 22, 2025 · PreprintCell Biology

Rapid and precise quantification of lymphocyte iron content by single cell inductively coupled plasma mass spectrometry

Philip Holdship, Megan R. Teh, Michalina Mazurczyk, Huei-Wen Chuang, Giulia Pironaci, Robert George Hilton, David Price, Jon Wade, Hal Drakesmith

The paper quantifies single-cell iron content in lymphocytes using ICP-MS and links iron levels to cellular activation and function.

bioRxiv · Nov 11, 2024 · PreprintImmunology

Iron deficiency causes aspartate-sensitive metabolic and proliferative dysfunction in CD8+ T cells

Megan R. Teh, Nancy Gudgeon, Joe N. Frost, Linda V. Sinclair, Alastair L. Smith, Christopher L. Millington, Barbara Kronsteiner, Jennie Roberts, Bryan P. Marzullo, Alexandra E. Preston, Jan Rehwinkel, Thomas A. Milne, Daniel A. Tennant, Susanna J. Dunachie, Andrew E. Armitage, , Hal Drakesmith

This study shows iron deficiency impairs CD8+ T cell proliferation and metabolism by disrupting mitochondrial function, but exogenous aspartate can rescue this defect.

bioRxiv · Feb 1, 2024 · PreprintImmunology