Integrating bacterial genomics and host transcriptomics links Burkholderia pseudomallei variation to melioidosis mortality and neutrophil responses
Arin Wongprommoon, Phumrapee Boonklang, Katie L Burnham…·Claire Chewapreecha
Author
Mahidol-Oxford Tropical Medicine Research Unit, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand;ORCID 0000-0001-5665-6293Unclaimed ORCID profile · follow to get notified of new preprints
3 papers
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Arin Wongprommoon, Phumrapee Boonklang, Katie L Burnham…·Claire Chewapreecha
Megan R. Teh, Nancy Gudgeon, Joe N. Frost…·Hal Drakesmith
This study shows iron deficiency impairs CD8+ T cell proliferation and metabolism by disrupting mitochondrial function, but exogenous aspartate can rescue this defect.
Manon Ragonnet‐Cronin, Rungtiwa Nutalai, Jiandong Huo…·Sakib Rokadiya
The paper identifies mutations in SARS-CoV-2 variants that confer resistance to monoclonal antibodies by analyzing genomic data and validating their impact on antibody neutralization.