Xu Zhang

Visualizing the M2 muscarinic acetylcholine receptor activation regulated by aromatic ring dynamics

This study uses atomic-level simulations to show how ligand binding modulates conformational dynamics of the M2 muscarinic receptor, revealing key aromatic residue interactions involved in activation.

MyoD is a structure organizer of 3D genome architecture in muscle cells

The paper shows MyoD organizes 3D genome architecture in muscle cells and demonstrates H3K27ac is insufficient for MyoD-induced chromatin loops.