Guohong Li

This study identifies DAXX as a regulator of LINE1 silencing during spermatogenesis in mice, showing its role in maintaining DNA methylation and preventing transposable element activation.

This study identifies NuMA's role in stabilizing linker histone H1 on chromatin to promote heterochromatin compaction and maintain epigenetic repression.

This study uses super-resolution imaging to show that replication origins are preferentially fired at the periphery of TADs due to chromatin re-organization linked to transcription and CTCF.

The paper shows MyoD organizes 3D genome architecture in muscle cells and demonstrates H3K27ac is insufficient for MyoD-induced chromatin loops.