Fei Wang

Temporal organization of shared brain states characterizes heterogeneity in major depressive disorder

This study identifies shared brain states in MDD and healthy controls using resting-state fMRI and hidden Markov modeling, revealing two distinct neurodynamic architectures associated with different symptom patterns.

Population-specific brain charts reveal Chinese-Western differences in neurodevelopmental trajectories

The paper develops population-specific brain charts for Chinese individuals, revealing distinct neurodevelopmental patterns compared to Western populations and showing better performance in predicting brain phenotypes.

Formaldehyde induces and promotes Alzheimer's disease pathologies in a 3D human neural cell culture system

This study shows that formaldehyde exposure increases Aβ40, Aβ42, and phosphorylated tau levels in 3D-cultured human neural cells, suggesting a role in Alzheimer's disease initiation and progression.

A longitudinal resource for population neuroscience of school-age children and adolescents in China

The paper introduces a longitudinal dataset of school-age children and adolescents in China, detailing its design, sampling, and neuroimaging measurements.

Single-cell multi-omic topic embedding reveals cell-type-specific and COVID-19 severity-related immune signatures

This study introduces moETM, a deep learning method for analyzing single-cell multi-omic data, and shows it identifies immune signatures and COVID-19 severity biomarkers.

AD-linked R47H-TREM2 mutation induces disease-enhancing proinflammatory microglial states in mice and humans

This study identifies R47H-TREM2 mutation-induced proinflammatory microglial states in human AD and tauopathy mice, showing Akt pathway involvement and potential therapeutic targets.