Yifei Yang

This study finds that the 16p11.2 microdeletion increases transcript level variation in human iPSC-derived forebrain interneuron progenitors, affecting gene regulation and potentially contributing to neurodevelopmental and metabolic phenotypes.

The paper uses single-cell Mendelian randomisation to identify cell-type specific genetic effects on brain disease and behaviour, revealing 118 genes with causal associations to 16 brain phenotypes.

This study investigates sex-specific effects of gut microbiome on bile acid metabolism by transplanting feces from male and female mice and measuring bile acid profiles and gene expression.

The paper identifies developing interneurons as a potential target for autism genetic risk factors by analyzing human and rodent neural data.

The paper identifies ALDOA and KIF22 as the only 16p11.2 transcripts enriched in human fetal cortical progenitors and hypothesizes their dosage changes may contribute to ASD in CNV patients.