Jose D. Herazo‐Maya

Myeloid HIF-1α Sustains Hypoxic Fibrotic Fronts and Drives Pulmonary Fibrosis

This study identifies myeloid HIF-1 as a driver of pulmonary fibrosis by sustaining hypoxic fronts and promoting fibroblast activation and matrix remodeling.

A 50-gene high-risk profile predictive of COVID-19 and Idiopathic Pulmonary Fibrosis mortality originates from a molecular imbalance in monocyte and T-cell subsets that reverses in survivors with post-COVID-19 Interstitial Lung Disease

The paper identifies a 50-gene high-risk profile predictive of mortality in COVID-19 and IPF, linked to monocyte and T-cell subset imbalances that reverse in post-COVID-19-ILD survivors.

A lung targeted miR-29 Mimic as a Therapy for Pulmonary Fibrosis

A stabilized miR-29 mimic, MRG-229, shows efficacy at lower doses and good safety in preclinical models, supporting its development for pulmonary fibrosis.

A repurposed, blood gene signature is associated with poor outcomes in SARS-CoV-2

The paper identifies a blood gene signature predictive of poor outcomes in SARS-CoV-2 infection by analyzing its cellular sources in single-cell data.