Genetic Risk of Reticular Pseudodrusen in Age-Related Macular Degeneration: HTRA1/lncRNA BX842242.1 dominates, with no evidence for Complement Cascade involvement
Samaneh Farashi, Carla J. Abbott, Brendan R. E. Ansell…·Melanie Bahlo
Author
Université de BordeauxORCID 0000-0002-8141-1543Unclaimed ORCID profile · follow to get notified of new preprints
8 papers
Recent·Most cited
Samaneh Farashi, Carla J. Abbott, Brendan R. E. Ansell…·Melanie Bahlo
Guido J. Falcone, Stacey Q Wolfe, Marialuisa Zedde…·the ERICH-Gene Investigators
ERICH-GENE collects and analyzes genomic and neuroimaging data from over 10,000 multi-ethnic ICH cases to identify genetic risk factors and trans-ethnic variation in ICH.
Cécile Duplàa, Valentin Delobel, Romain Boulestreau…·Claire R. Peghaire
This study identifies TRIM47 as a genetic determinant of cerebral small vessel disease, showing it regulates brain homeostasis through the NRF2 antioxidant pathway by stabilizing NRF2 protein levels.
Maria J. Knol, Raymond A. Poot, Tavia E. Evans…·Saud Alhusaini
This study identifies 67 genetic loci associated with head size, finding strong overlaps with cancer pathways and genes, suggesting shared genetic mechanisms between head growth and cancer risk.
Muralidharan Sargurupremraj, Aïcha Soumaré, Joshua C. Bis…·Stéphanie Debette
This paper uses genetic data to investigate the causal relationships between vascular traits like white matter hyperintensity, blood pressure, and stroke with dementia and Alzheimer's disease risk.
Bernard Fongang, Muralidharan Sargurupremraj, Xueqiu Jian…·Sudha S. Seshadri
This study performs a meta-analysis of GWAS to identify new genetic loci associated with all-cause and vascular dementia, revealing shared and distinct risk factors.
Edith Hofer, Gennady V. Roshchupkin, Hieab H.H. Adams…·Marcio Almeida
The paper identifies 161 genome-wide significant genetic associations for cortical structure traits across 34 brain regions, highlighting key biological pathways and gene functions.
Jean Shin, Shaojie Ma, Edith Hofer…·Shareefa Dalvie
The paper identifies genetic associations with cortical surface area using PCA and GWAS, linking DAAM1 to visual cortex development through mitochondrial pathways and thalamocortical input.