Author

Cécile Duplàa

InsermORCID 0000-0001-8003-3969Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Approach:experimental assay· 2 Organism:mouse· 2 Research Focus:development & morphogenesis· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Research Focus:gene regulatory network inference· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

Claire R. PeghaireiD· 2 shared Juliette Vaurs· 2 shared Romain BoulestreauiD· 2 shared Sébastien RubiniD· 2 shared Thierry CouffinhaliD· 2 shared Alexandre BoyeriD· 1 shared Aniket MishraiD· 1 shared Arthur OrieuxiD· 1 shared

Activity by Year

2024-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 39 mutual co-author links

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2 shared papersPathology

Claire R. PeghaireORCID

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2 papers

Recent·Most cited

PathologybioRxivPreprintMar 24, 2025

Strain Matters: The 129S1/SvlmJ Mouse Model Reveals the Genetic and Inflammatory Susceptibility to Hypertensive Complications

Arthur Orieux, Romain Boulestreau, Marie‐Lise Bats…·Sébastien Rubin

This study compares two mouse strains to show that genetic background affects susceptibility to hypertensive complications, with 129S1/SvlmJ mice showing more severe organ damage and inflammation.

DOI 10.1101/2025.03.24.641145

mousebulk RNA-seq

𝕏 PostBluesky

NeurosciencebioRxivPreprintOct 8, 2024

Cerebral Small Vessel Disease genetic determinant TRIM47 controls brain homeostasis via the NRF2 antioxidant system

Cécile Duplàa, Valentin Delobel, Romain Boulestreau…·Claire R. Peghaire

This study identifies TRIM47 as a genetic determinant of cerebral small vessel disease, showing it regulates brain homeostasis through the NRF2 antioxidant pathway by stabilizing NRF2 protein levels.

3 citations

mousebulk RNA-seq

𝕏 PostBluesky