Norberto Peporine Lopes

Ecological Interactions Drive Metabolomic Diversification in Amazonian Pseudonocardia Symbionts

This study examines metabolomic diversity in Amazonian Pseudonocardia bacteria, showing that ecological interactions and local adaptation drive chemical variation rather than phylogeny.

Semi-automated monitoring of longitudinal microbial metabolic dynamics: A study case for lignin degradation

This paper presents a low-cost bioreactor system for monitoring microbial metabolic dynamics in lignin degradation studies using two fungal species.

Characterization of a marine bacteria through a novel metabologenomics approach

The paper characterizes a marine bacteria using a metabologenomics approach, linking genomic and metabolomic data to identify a new biosynthetic gene cluster and bioactive compound.

Optimizing the detection of biological signals through a semi-automated feature selection tool

The paper introduces RegFilter, a tool that enhances metabolite detection in DDA mode by dynamically selecting precursor ions and creating custom spectral libraries.

Improving annotation propagation on molecular networks through random walks: Introducing ChemWalker

The paper introduces ChemWalker, a method that improves annotation propagation on molecular networks using random walks, enhancing scalability and efficiency compared to previous approaches.

Meningeal dendritic cells-astrocytes interactions elevate the kynurenine metabolic pathway to sustain neuropathic pain

This study identifies the kynurenine metabolic pathway as a key factor in sustaining neuropathic pain through interactions between meningeal dendritic cells and astrocytes.

Reference data based insights expand understanding of human metabolomes

This paper expands the interpretability of human metabolomes by using food-based annotations, increasing the fraction of molecular features understood 7-fold.

Exploring integument transcriptomes, cuticle ultrastructure, and cuticular hydrocarbons profiles in eusocial and solitary bee species displaying heterochronic adult cuticle maturation

The paper compares integument transcriptomes, cuticle ultrastructure, and cuticular hydrocarbon profiles between eusocial and solitary bees to investigate cuticle maturation heterochrony.