Author
InsermORCID 0000-0002-8181-4721Unclaimed ORCID profile · follow to get notified of new preprints
3 papers
Recent·Most cited
Maxime Carpentier, Mohyeddine Omrane, Rola Shaaban…·Abdou Rachid Thiam
This study shows that seipin regulates CAV1 trafficking and organelle interactions by controlling lipid metabolism and membrane order, impacting cellular homeostasis and metabolic disorders.
Vahid Aslanzadeh, Gemma V. Brierley, Rupa Kumar…·Robert K. Semple
The paper uses deep mutational scanning to assess the functional impact of INSR variants, identifying clinically relevant function scores and potential gain-of-function variants.
Jérémie Gautheron, Christophe H.P. Morisseau, Wendy K. Chung…·Isabelle Jéru
The paper identifies EPHX1 mutations causing lipoatrophic diabetes through impaired epoxide hydrolysis and increased cellular senescence, with metreleptin therapy showing benefit.