Author

Zhihao Guo

Chinese University of Hong KongORCID 0000-0002-8186-8447Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biochemistry· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Assay:proteomics· 2 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Research Focus:protein structure prediction· 1

Frequent Co-Authors

Anne Jackson· 1 shared B. K.W. NG· 1 shared Bowen MaiD· 1 shared David Chaim RubinszteiniD· 1 shared Dean W. FelsheriD· 1 shared Jialin LiuiD· 1 shared Khadija Shahed KhaniD· 1 shared Reham M. AlsaadiiD· 1 shared

Activity by Year

2019-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperMolecular Biology

Anne Jackson

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2 papers

Recent·Most cited

BiochemistryCell chemical biologyPeer-reviewedSep 1, 2026

Rewiring c-Myc Transcriptional Activity with an O-GlcNAcylation Targeting Chimera (OGTAC)

Tongyang Xu, Zhihao Guo, Khadija Shahed Khan…·B. K.W. NG

This paper introduces OGTAC, a molecule that enhances c-Myc O-GlcNAcylation, rewires its transcriptional activity, and inhibits cancer cell proliferation.

2 citationstop 5%

humanproteomics

Molecular BiologyEMBO ReportsPeer-reviewedMay 24, 2019

ULK-mediated phosphorylation of ATG16L1 promotes xenophagy, but destabilizes the ATG16L1 Crohn’s mutant

Reham M. Alsaadi, Truc T. Losier, Wensheng Tian…·Ryan Charles Russell

This study shows ULK1 phosphorylates ATG16L1, enhancing wildtype function but destabilizing the Crohn’s disease-associated mutant, thereby affecting xenophagy.

66 citationstop 3%

humanproteomics