Núria Bonifaci

This study shows that loss of miR-424(322)~503 worsens colon cancer in PTEN-deficient mice by activating MAPK and TGFβ pathways.

This study uses multiplexed CRISPR/Cas9 to edit multiple tumor suppressor genes in mouse endometrium, creating models of high-risk endometrial cancers with molecular and histological features similar to human tumors.

This study shows that miR-424(322)~503 cluster promotes endometrial cancer progression driven by PTEN deficiency by enhancing proliferation and blocking TGFβ-mediated apoptosis.

This study evaluates the ability of a polygenic risk score to refine colorectal cancer risk in Lynch syndrome individuals, finding weak associations in specific subgroups.