Author
ORCID 0000-0002-8195-3668Unclaimed ORCID profile · follow to get notified of new preprints
4 papers
Recent·Most cited
Dhana Sekhar Reddy Bandi, Ganji Purnachandra Nagaraju, Sujith Sarvesh…·Bassel F. El‐Rayes
Oral PDE10 inhibitor ADT-030 curbed KRAS-mutant pancreatic cancer growth and metastasis in mouse models, stayed active in KRAS-inhibitor-resistant cells, and shifted tumor immune profiles.
Yan Xiong, Liqing Wang, Martina Minisini…·Wayne W. Hancock
This study shows that inhibiting CHD4, a component of the NuRD complex, reduces Treg cells and enhances antitumor immunity without causing autoimmunity.
George Merhej, Gurusankar Ramamoorthy, Danda P. Chapagai…·Campbell McInnes
This study develops and characterizes abbapolins, non-peptidic PLK1 PBD inhibitors, showing in vivo efficacy against prostate cancer and synergy with enzalutamide.
Ivan Babić, Nikolas Bryan, Claire Cunningham…·Elmar Nurmemmedov
The paper introduces a fluorescence-based method to quantify drug-target engagement in temperature series using split-RNase S complementation.