Wayne W. Hancock

This study shows that inhibiting CHD4, a component of the NuRD complex, reduces Treg cells and enhances antitumor immunity without causing autoimmunity.

This study compares selective APRIL and dual APRIL/BAFF inhibition in mice and humans, finding that dual blockade more severely disrupts B-cell maturation and immune protection.

This study shows that Mbd2 deficiency in mice leads to cognitive and social deficits, altered gene expression, and DNA methylation patterns similar to those in ASD, suggesting Mbd2 is an epigenetic regulator of ASD-risk genes.