Cell BiologyeLifePeer-reviewed
Dissociation of the nuclear basket triggers chromosome loss in aging yeast
Mihailo Mirkovic, Jordan McCarthy, Anne C. Meinema…·Yves Barral
This study shows that nuclear basket displacement in aging yeast causes chromosome loss by disrupting pre-mRNA quality control and asymmetric segregation.
DOI 10.7554/elife.104530.3