Julien Colombani

Higher-Order Mechanical Neighbourhood Sensing Governs Cell Fate in Complex Tissues

The paper identifies a higher-order mechanical neighbourhood-sensing mechanism in Drosophila midgut that integrates cell identity and mechanics to regulate stem cell fate.

Pvf1-PvR-mediated crosstalk between the trachea and the gut guides intestinal stem cell migration to promote gut regeneration.

This study identifies Pvf1-PvR signaling between the trachea and gut that guides intestinal stem cell migration during regeneration.

Dilp8 controls a time window for tissue size adjustment in Drosophila

This study identifies Dilp8 as a hormone that establishes a time window for tissue size adjustment in Drosophila, ensuring bilateral symmetry by buffering developmental noise.

Inter-organ growth coordination is mediated by the Xrp1/Dilp8 axis in Drosophila

The paper shows that the Xrp1/Dilp8 axis coordinates inter-organ growth in Drosophila by linking organ growth status to systemic responses.