Joseph M. Fox

Delayed Tagging of ED-A Fibronectin-Mimetic Peptide in an RGD-Decorated Synthetic Matrix Induces Fibroblast-to-Myofibroblast Transition

This study shows that delayed introduction of EDG in an RGD-decorated hydrogel promotes fibroblast-to-myofibroblast transition by increasing myofibroblast markers and ECM proteins.

Bioorthogonal Tuning of Hydrogel Stiffness Promotes Zonal Redifferentiation of Passaged Chondrocytes

This study shows that tunable hydrogels can enhance zone-specific chondrocyte phenotypes and promote zonally organized cartilage formation.

Time-Resolved Tracking and Secretome Mapping of Intracellular, Cell Surface, and Extracellular Glycoconjugates with a Mini-Tetrazine N-Acetylglucosamine

This paper introduces HTz-GlcNAc, a tool for real-time tracking of glycoconjugates and secretome mapping in live cells.

TGFβ1 and RGD Cooperatively Regulate SMAD 2/3 Mediated Oncogenic Effects in Prostate Cancer Cells in Bioorthogonally Constructed Hydrogels

This study shows that TGFβ1 and RGD peptides work together to drive aggressive behavior in prostate cancer cells using a 3D hydrogel model.

The Legionella pneumophila peptidoglycan recycling kinase, AmgK, is essential for survival and replication inside host alveolar macrophages

This study shows that AmgK, a peptidoglycan kinase in Legionella pneumophila, is essential for intracellular survival and replication in host macrophages, highlighting its role in pathogenicity and potential as a drug target.