Author

Kimie Tanaka

Juntendo UniversityORCID 0000-0002-8261-1854Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Neuroscience· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1 Organism:human· 1 Approach:statistical model· 1

Frequent Co-Authors

Atsushi HoriiD· 1 shared Corina RosalesiD· 1 shared Faith Jessica ParaniD· 1 shared Haruka Inaba· 1 shared Mizuho Okamoto· 1 shared Nagomi KurebayashiiD· 1 shared Shoichi Sato· 1 shared Takashi HatoiD· 1 shared

Activity by Year

2023-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperNeuroscience

Atsushi HoriORCID

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1 paper

Recent·Most cited

Carvedilol suppresses ryanodine receptor-dependent Ca2+ bursts in human neurons bearing PSEN1 variants found in early onset Alzheimer's disease

Atsushi Hori, Tomohiko Ai, Takashi Hato, Haruka Inaba, Kimie Tanaka, Shoichi Sato, Mizuho Okamoto, Yuna Horiuchi, Faith Jessica Paran, Yoko Tabe, Corina Rosales, Wado Akamatsu, Takashi Murayama, Nagomi Kurebayashi, Takashi Sakurai, Takashi Miida

The paper shows that PSEN1 variants in early-onset Alzheimer's disease cause abnormal Ca2+ bursts in neurons via RyR2, which can be suppressed by carvedilol.

bioRxiv · Sep 15, 2023 · PreprintNeuroscience