Cancer BiologybioRxivPreprint
Targeting tGLI1, a novel mediator of tumor therapeutic resistance, using Ketoconazole sensitizes glioblastoma to CDK4/6 therapy and Chemoradiation
Yu Pu Yang, Austin Arrigo, Ankush Chandra…·Hui‐Wen Lo
This paper identifies tGLI1 as a mediator of GBM resistance to CDK4/6 inhibitors and shows that ketoconazole sensitizes GBM to CDK4/6 therapy and chemoradiation.
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