Hui‐Wen Lo

This study shows RET is highly activated in breast cancer brain metastases and that RET inhibitors reduce metastasis and tumor growth in preclinical models.

This study identifies miR-425 in breast cancer extracellular vesicles as a driver of brain metastasis by activating astrocytes through the miR-425-ZNF24-CCL8 signaling axis.

This paper identifies tGLI1 as a mediator of GBM resistance to CDK4/6 inhibitors and shows that ketoconazole sensitizes GBM to CDK4/6 therapy and chemoradiation.