Author

Jay‐Jiguang Zhu

The University of Texas Health Science Center at HoustonORCID 0000-0003-4635-0914Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

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Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Approach:deep learning· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Assay:imaging· 1

Frequent Co-Authors

Anam Nazir· 1 shared Ankush ChandraiD· 1 shared Antonio DonoiD· 1 shared Arif O. HarmanciiD· 1 shared Austin ArrigoiD· 1 shared Chuling ZhuangiD· 1 shared Dongqin ZhuiD· 1 shared Hui‐Wen LoiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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1 shared paperNeuroscience

Anam Nazir

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Author profile →

2 papers

Recent·Most cited

GlioVision: A Multi-Modal MRI Framework for Non-Invasive Glioma Molecular Biomarkers Prediction

Anam Nazir, Muhammad Nadeem Cheema, Yu‐Chun Hsu, Xiaoqian Jiang, Jay‐Jiguang Zhu, Arif O. Harmanci

GlioVision predicts four glioma molecular biomarkers from MRI data using a multi-modal framework, achieving high AUC scores across multiple cohorts.

Magnetic Resonance Imaging · Oct 28, 2026Peer-reviewedNeuroscience

Targeting tGLI1, a novel mediator of tumor therapeutic resistance, using Ketoconazole sensitizes glioblastoma to CDK4/6 therapy and Chemoradiation

Yu Pu Yang, Austin Arrigo, Ankush Chandra, Chuling Zhuang, Mariana K. Najjar, Munazza Samar Khan, Dongqin Zhu, Antonio Dono, Roy Ervin Strowd III, Nitin Tandon, Jay‐Jiguang Zhu, Sigmund H. Hsu, Yoshua Esquenazi, Michael David Chan, Hui‐Wen Lo

This paper identifies tGLI1 as a mediator of GBM resistance to CDK4/6 inhibitors and shows that ketoconazole sensitizes GBM to CDK4/6 therapy and chemoradiation.

bioRxiv · Feb 20, 2025 · PreprintCancer Biology