M1-linked Ubiquitination by LUBAC Regulates AMPK Activity and the Response to Energetic Stress
Camilla Reiter Elbæk, Sophie Gradinaru, Anna M. Dahlström, Alexander Frueh, Akhee Sabiha Jahan, Joyceline Cuenco, Anna L. Aalto, John Rizk, Simon A. Hawley, Sarah N. J. Franks, Michael Stumpe, Srinivasa Prasad Kolapalli, Chris Kedong Wang, Cara J. Ellison, Ximena Hildebrandt, , Rune Busk Damgaard
This study shows LUBAC activates AMPK and OTULIN restricts it, affecting metabolic responses to energy stress in cells, mice, and flies.
Cell Death and Differentiation · Feb 13, 2026Peer-reviewedCell Biology