Katrin Schrenk-Siemens

The paper identifies hypothalamic preoptic neurons that develop warm-sensitive activity during heat acclimation, enabling heat tolerance through cell-autonomous mechanisms.

This study shows that spinal astrocytic glycogen dynamics, regulated by PTG, are critical for maintaining persistent pain through neuronal plasticity and metabolic coupling with neurons.

The paper generates hESC-derived nociceptor-like cells and shows they exhibit mechano-nociceptive characteristics requiring PIEZO2 for mechanotransduction.