Author

Isaac Hodes

Icahn School of Medicine at Mount SinaiORCID 0000-0002-8305-9045Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioinformatics· 5

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:software / tool· 3 Assay:bulk RNA-seq· 2 Organism:human· 2 Research Focus:variant calling· 2 Assay:whole-exome sequencing· 2 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

Jeff HammerbacheriD· 4 shared Bülent Arman AksoyiD· 3 shared Alex RubinsteyniD· 2 shared Dan VanderkamiD· 2 shared Jaclyn Perrone· 2 shared Julia KodyshiD· 2 shared Sébastien MondetiD· 2 shared B. Arman Aksoy· 1 shared

Activity by Year

2016-2018 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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4 shared papersBioinformatics

Jeff HammerbacherORCID

Mutual co-authors in cluster

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5 papers

Recent·Most cited

BioinformaticsbioRxivPreprintOct 18, 2018

Vaxrank: A Computational Tool For Designing Personalized Cancer Vaccines

Alex Rubinsteyn, Isaac Hodes, Julia Kodysh, Jeff Hammerbacher

Vaxrank selects neoantigen vaccine peptides from tumor mutations, RNA data, and HLA type to design personalized cancer vaccines.

37 citations

humanbulk RNA-seq

𝕏 PostBluesky

BioinformaticsFrontiers in ImmunologyPeer-reviewedJan 18, 2018

Computational pipeline for the PGV-001 neoantigen vaccine trial

Alex Rubinsteyn, Julia Kodysh, Isaac Hodes…·Jeff Hammerbacher

The paper describes a computational pipeline for a personalized neoantigen vaccine trial, including tools for variant calling, peptide selection, and sequence reconstruction.

74 citations

humanwhole-exome sequencing

𝕏 PostBluesky

BioinformaticsbioRxivPreprintNov 7, 2017

Bioinformatics Workflow Management With The Wobidisco Ecosystem

Sébastien Mondet, Bülent Arman Aksoy, Leonid Rozenberg…·Jeff Hammerbacher

The paper introduces a set of open-source workflow management tools for bioinformatics, emphasizing reliability and flexibility.

6 citations

experimental assaysoftware / tool

𝕏 PostBluesky

BioinformaticsbioRxivPreprintApr 6, 2017

Cycledash: a web application for the interactive analysis and exploration of variants

Isaac Hodes, Dan Vanderkam, Tavi Nathanson…·Jeff Hammerbacher

Cycledash provides a web tool for validating and analyzing somatic variants by integrating existing tools and workflows.

DOI 10.1101/125153

whole-exome sequencingexperimental assay

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BioinformaticsBioinformaticsPeer-reviewedMar 29, 2016

pileup.js: a JavaScript library for interactive and in-browser visualization of genomic data

Dan Vanderkam, B. Arman Aksoy, Isaac Hodes…·Jeffrey Hammerbacher

pileup.js provides an interactive, browser-based genomic data visualization tool for variant evidence investigation within web applications.

DOI 10.1093/bioinformatics/btw167

experimental assaysoftware / tool

𝕏 PostBluesky