NeurosciencebioRxivPreprint
Mutations on a novel brain-specific isoform of PGC1α leads to extensive upregulation of neurotransmitter-related genes and sexually dimorphic motor deficits in mice
Oswaldo A. Lozoya, Fu‐Hua Xu, Dagoberto Grenet…·Richard P. Woychik
This study shows that a brain-specific PGC1α isoform mutation causes motor deficits and gene upregulation in female mice, suggesting a role in female-specific transcriptional programs.
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