Author

Richard J. Bryant

University of OxfordORCID 0000-0002-8330-9251Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Genomics· 2 Bioinformatics· 1

Signature Assays, Organisms & Methods

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Organism:human· 3 Approach:statistical model· 3 Assay:bulk RNA-seq· 2 Research Focus:differential expression· 2 Assay:spatial transcriptomics· 2 Research Focus:benchmarking· 1 Assay:DNA methylation· 1 Approach:experimental assay· 1

Frequent Co-Authors

Ian Geoffrey MillsiD· 3 shared Alastair D.G. LambiD· 2 shared Dan J. WoodcockiD· 2 shared Dimitrios DoultsinosiD· 2 shared Freddie Charles HamdyiD· 2 shared Ninu PouloseiD· 2 shared Olivier CussenotiD· 2 shared Sandy FigieliD· 2 shared

Activity by Year

2023-2023 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 42 mutual co-author links

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3 shared papersGenomics

Ian Geoffrey MillsORCID

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3 papers

Recent·Most cited

GenomicsbioRxivPreprintSep 4, 2023

Molecular analysis of archival diagnostic prostate cancer biopsies identifies genomic similarities in cases with progression post-radiotherapy, and those with de novo metastatic disease.

Philip Vincent Charlton, Dawn O’Reilly, Yiannis Philippou…·Richard J. Bryant

DOI 10.1101/2023.09.04.555868

humanbulk RNA-seq

BioinformaticsbioRxivPreprintFeb 26, 2023

Clonal phylogenies inferred from bulk, single cell, and spatial transcriptomic analysis of cancer

Andrew M. Erickson, Sandy Figiel, Timothy Rajakumar…·Alastair D.G. Lamb

The paper evaluates the accuracy of transcript-based inferred tumor phylogenies compared to DNA-based phylogenies in prostate cancer using single-cell, spatial transcriptomic, and bulk data.

2 citations

humanbulk RNA-seq

GenomicsEuropean UrologyPeer-reviewedFeb 1, 2023

Spatial transcriptomic analysis of virtual prostate biopsy reveals confounding effect of heterogeneity on genomic signature scoring

Sandy Figiel, W. Yin, Dimitrios Doultsinos…·Alastair D. Lamb

The paper uses spatial transcriptomic data to show that bulk genomic signature scoring in prostate cancer biopsies is confounded by tumour heterogeneity, leading to inaccurate risk assessments.

DOI 10.1016/s0302-2838(23)01273-3

humanspatial transcriptomics