Author

Alastair D. Lamb

University of Oxford

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1 Genomics· 1

Signature Assays, Organisms & Methods

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Research Focus:differential expression· 2 Approach:experimental assay· 2 Organism:human· 2 Research Focus:benchmarking· 1 Research Focus:cell type annotation· 1 Research Focus:clustering· 1 Research Focus:gene regulatory network inference· 1 Assay:scRNA-seq· 1

Frequent Co-Authors

A. Magnussen· 1 shared A.M. Erickson· 1 shared Arnoud J. TempletoniD· 1 shared Ashkan MortezaviiD· 1 shared Clare Verrill· 1 shared Clémentine Le MagneniD· 1 shared Cyrill A. RentschiD· 1 shared Dan J. WoodcockiD· 1 shared

Activity by Year

2023-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperGenomics

A. Magnussen

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

ECM-free patient-derived organoids preserve diverse prostate cancer lineages and uncover in vitro-enriched cell types

Robin Dolgos, Romuald Parmentier, Jing Wang, Raphaëlle Servant, Arnoud J. Templeton, Tobias Zellweger, Alastair D. Lamb, Kirsten D. Mertz, Svetozar Subotic, Tatjana Vlajnic, Hans‐Helge Seifert, Ashkan Mortezavi, Cyrill A. Rentsch, Lukas Bubendorf, Clémentine Le Magnen

This study develops an ECM-free culture system for prostate cancer organoids, revealing diverse tumor lineages and identifying in vitro-enriched cell types through single-cell RNA sequencing.

Cell Reports · Oct 1, 2025Peer-reviewedCancer Biology

Spatial transcriptomic analysis of virtual prostate biopsy reveals confounding effect of heterogeneity on genomic signature scoring

Sandy Figiel, W. Yin, Dimitrios Doultsinos, A.M. Erickson, Ninu Poulose, Roshan Ajeet Singh, A. Magnussen, Thineskrishna Anbarasan, Renuka Teague, Mengxiao He, Joakim Lundeberg, Massimo F. Loda, Clare Verrill, Richard Colling, Pelvender S. Gill, , Alastair D. Lamb

The paper uses spatial transcriptomic data to show that bulk genomic signature scoring in prostate cancer biopsies is confounded by tumour heterogeneity, leading to inaccurate risk assessments.

European Urology · Feb 1, 2023Peer-reviewedGenomics