S. Randal Voss

Dissecting functional elements in giant genomes using the first generation of high quality salamander assemblies

The paper generates a high-quality axolotl genome assembly and identifies conserved non-coding elements linked to regeneration and cis-regulatory functions.

Do organisms need an impact factor? Citations of key biological resources including model organisms reveal usage patterns and impact.

The paper analyzes citation practices for biological resources over 10 years, showing improved findability and adherence to NIH rigor criteria after adopting RRID citations.

Retinoic acid breakdown is required for proximodistal positional identity during amphibian limb regeneration

This study shows that retinoic acid breakdown via CYP26B1 determines positional identity during amphibian limb regeneration, with Shox playing a key role in PD skeletal element formation.

Model-free Identification of Phenotype-Relevant Variables From Dose Response Data

The paper identifies phenotype-relevant genes by analyzing dose response data without using models, finding genes with spikes in transcriptional sensitivity that likely regulate phenotypic transitions.

Building model prototypes from time-course data

The paper introduces a method to build model prototypes from time-course data using discrete functions and wiring diagrams, applied to gene expression data from salamander tail regeneration.

A Chromosome-Scale Assembly of the Enormous (32 Gb) Axolotl Genome

This paper presents a chromosome-scale assembly of the axolotl genome, enabling large-scale genomic analyses and resolving orthologies and phenotypic features.

Miniscule differences between the sex chromosomes in the giant genome of a salamander, Ambystoma mexicanum

The paper identifies a tiny W-specific region in the axolotl genome containing a duplicated ATRX gene, suggesting it as a candidate for the sex-determining locus or a sexually antagonistic gene.