Met/HGFR triggers detrimental reactive microglia in TBI
Rida Rehman, Michael Miller, Sruthi Sankari Krishnamurthy, Jacob Kjell, Lobna Elsayed, Stefanie M. Hauck, Florian olde Heuvel, Alison Conquest, Akila Chandrasekar, Albert Christian Ludolph, Tobias M. Boeckers, Medhanie Assmelash Mulaw, Magdalena Goetz, Maria Cristina Morganti-Kossmann, Aya Takeoka, Francesco Roselli
This study identifies cMet/HGFR as a modulator of early neuroinflammation in TBI, showing that its inhibition reduces microglial reactivity and improves recovery.
Cell Reports · Dec 1, 2022Peer-reviewedNeuroscience