Author
Universität UlmORCID 0000-0002-2501-6952Unclaimed ORCID profile · follow to get notified of new preprints
8 papers
Recent·Most cited
Ziwei Du, Lilli Weber, Ulrike F.G. Buettner, Melanie Gerstenlauer, Uta Manfras, Katja Steiger, Thomas Metzler, Lap Kwan Chan, Medhanie Assmelash Mulaw, Miltiadis Tsesmelis, Thomas Wirth
This study shows that NIK stabilization causes chronic pancreatitis and pancreatic lipomatosis via RelB-dependent non-canonical NF-κB signaling.
bioRxiv · Oct 14, 2026 · PreprintCancer Biology
Maria Carolina Florian, Amanda Amoah, Kalpana Nattamai, Karin Soller, Angelika Vollmer, Markus Hoenicka, Andreas Liebold, Katharina Bauer, Jan‐Philipp Mallm, Hartmut Geiger, Medhanie Assmelash Mulaw
The paper uses single-cell RNA sequencing to analyze somatic mutations in HSCs and finds age-related clonal expansion and transcriptional divergence.
bioRxiv · Jan 26, 2026 · PreprintGenomics
Julian Niemann, Selina Stahl, Vadim Sakk, Juan-Felipe Perez-Correa, Wolfgang Wagner, Andrea Jaensch, Dietrich Rothenbacher, Yi Zheng, Medhanie Assmelash Mulaw, Hartmut Geiger, Mona Vogel
This study shows that the level of myeloid skewing in blood correlates with biological aging and disease in mice and humans.
bioRxiv · Jan 22, 2026 · PreprintCell Biology
Miltiadis Tsesmelis, Rebecca Andersson, Alba Ferrer-Pérez, Sara Montserrat‐Vazquez, Maria Carolina Florian, Medhanie Assmelash Mulaw
The paper uses deep learning to link TP53 genotype with expression-defined transcriptional programs in AML, finding a strong correlation between p53-low expression and TP53-inactive genotypes.
bioRxiv · Nov 10, 2025 · PreprintBioinformatics
Élodie Roger, Hannah M Mummey, Eleni Zimmer, Dharini Srinivasan, Anna Härle, Loïc Moubri, Alica K. Beutel, Rima Singh, Menar Ekizce, Michael Karl Melzer, Yun Jung Lee, Austin Silva, Luisa Härle, Thomas Engleitner, Frank Arnold, , Alexander Kleger
This study shows that ATM-deficient pancreatic cancers reprogram the tumor microenvironment via TGF-β-driven myCAF enrichment, and targeting this stromal axis with chemotherapy improves therapeutic efficacy.
bioRxiv · Sep 16, 2025 · PreprintCancer Biology
Laura Meier, Medhanie Assmelash Mulaw, Verena Durner, Luca Schäfer, Carlos Schönfeldt‐Lecuona, Verena Bopp, Heiko Graf, Markus Otto, Petra Steinacker, Henning Großkopf, Karin M. Danzer
The paper identifies a monocyte dysregulation signature in MDD linked to clinical symptoms using CITE-Seq data from PBMCs.
bioRxiv · Aug 12, 2025 · PreprintGenomics
Rida Rehman, Michael Miller, Sruthi Sankari Krishnamurthy, Jacob Kjell, Lobna Elsayed, Stefanie M. Hauck, Florian olde Heuvel, Alison Conquest, Akila Chandrasekar, Albert Christian Ludolph, Tobias M. Boeckers, Medhanie Assmelash Mulaw, Magdalena Goetz, Maria Cristina Morganti-Kossmann, Aya Takeoka, Francesco Roselli
This study identifies cMet/HGFR as a modulator of early neuroinflammation in TBI, showing that its inhibition reduces microglial reactivity and improves recovery.
Cell Reports · Dec 1, 2022Peer-reviewedNeuroscience
Alberto Bertozzi, Chi Chung Wu, Phong D. Nguyen, Mohankrishna Dalvoy Vasudevarao, Medhanie Assmelash Mulaw, Charlotte D. Koopman, Teun P. de Boer, Jeroen Bakkers, Gilbert Weidinger
The paper quantifies cardiomyocyte regeneration in zebrafish after injury, finding complete numerical replacement but incomplete differentiation and scar resorption.
Developmental Biology · Dec 10, 2020Peer-reviewedDevelopmental Biology