Author

George Plitas

Memorial Sloan Kettering Cancer CenterORCID 0000-0002-8357-9534Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioinformatics· 2 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:deep learning· 2 Organism:human· 2 Organism:mouse· 2 Assay:spatial transcriptomics· 2 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

Achille NazaretiD· 2 shared Elham AziziiD· 2 shared Alexander Yu RudenskyiD· 1 shared Ashley M. SidebottomiD· 1 shared Attila GácseriD· 1 shared Audrey Billips· 1 shared Bahawar S. DhilloniD· 1 shared Cameron Y. ParkiD· 1 shared

Activity by Year

2022-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 18 mutual co-author links

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2 shared papersBioinformatics

Achille NazaretORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

AMICI: Attention Mechanism Interpretation of Cell-cell Interactions

Justin Hong, Khushi Desai, Tu Duyen Nguyen, Achille Nazaret, Nathan Levy, Can Ergen, George Plitas, Elham Azizi

AMICI estimates cell-cell interaction length scales and links communication to gene programs in spatial transcriptomic data.

bioRxiv · Sep 22, 2025 · PreprintBioinformatics

Intracellular acidification by bacteria-derived valeric acid is a mechanism of trans-kingdom ecology against Candida parapsilosis colonization

Keiko Yasuma-Mitobe, Chen Liao, Tibor Németh, Kevin P. Byrne, Audrey Billips, Ruben Jose Jesus Faustino Ramos, Cristine Nicole Salinas, Eric Chan, Martina Perissinoto, Ashley M. Sidebottom, George Plitas, Geraldine Butler, Justin R. Cross, Eric G. Pamer, Attila Gácser, , Tobias M. Hohl

The paper uses machine learning to identify valeric acid as a bacterial metabolite that inhibits Candida parapsilosis growth through intracellular acidification, reducing fungal colonization in mice.

bioRxiv · Sep 12, 2025 · PreprintMicrobiology

Starfysh reveals heterogeneous spatial dynamics in the breast tumor microenvironment

Siyu He, Yinuo Jin, Achille Nazaret, Lingting Shi, Xueer Chen, Sham Rampersaud, Bahawar S. Dhillon, Izabella K. Valdez, Lauren E Friend, Joy Linyue Fan, Cameron Y. Park, Rachel L. Mintz, Yeh‐Hsing Lao, David Carrera, Kaylee W Fang, , Elham Azizi

Starfysh integrates spatial transcriptomics and histology to analyze tumor microenvironments, identifying disease-specific spatial hubs and immune interactions in breast cancers.

bioRxiv · Nov 21, 2022 · PreprintBioinformatics