Tobias M. Hohl

This study shows that GM-CSF signaling in CCR2+ cells is essential for killing Aspergillus fumigatus and host survival during pulmonary infection.

This study shows that ampicillin treatment impairs neutrophil-mediated immunity to Aspergillus fumigatus in mice, increasing mortality and fungal burden.

The paper uses machine learning to identify valeric acid as a bacterial metabolite that inhibits Candida parapsilosis growth through intracellular acidification, reducing fungal colonization in mice.

The paper identifies an IFN-STAT1-CYBB axis that mediates protective crosstalk between plasmacytoid dendritic cells and neutrophils during Aspergillus fumigatus infection.

This study identifies GM-CSF produced by SPC+ epithelial cells as critical for neutrophil-mediated immunity against Aspergillus fumigatus, enhancing fungal killing and host survival.

This study shows perforin-2 is not essential for antifungal immunity against A. fumigatus and C. albicans in immune-competent mice, emphasizing the need for co-housed littermate controls.

This study identifies that resistance to miltefosine in Candida parapsilosis arises from RTA3 gene amplification or flippase inactivation, altering plasma membrane lipid asymmetry.

The paper customizes a DADA2-based pipeline for fungal ITS1 amplicon datasets to improve species-level taxonomic annotation accuracy in clinical samples.

The paper identifies a new C. metapsilosis isolate resulting from a separate hybridization event, showing distinct genomic features compared to previously known isolates.