Author

Chukwuma A. Agu

Wellcome Sanger InstituteORCID 0000-0002-8368-4457Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:human· 3 Research Focus:differential expression· 2 Approach:statistical model· 2 Research Focus:benchmarking· 1 Research Focus:eQTL / molecular QTL mapping· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Assay:proteomics· 1

Frequent Co-Authors

Alex Alderton· 2 shared Andreas LehaiD· 2 shared Ângela GonçalvesiD· 2 shared Angus I. LamondiD· 2 shared Anja Kolb‐Kokocinski· 2 shared Christopher M. Kirton· 2 shared Dalila BensaddekiD· 2 shared Daniel D. SeatoniD· 2 shared

Activity by Year

2020-2021 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersGenomics

Alex Alderton

Mutual co-authors in cluster

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3 papers

Recent·Most cited

GenomicsNature CancerPeer-reviewedApr 26, 2021

Dissecting mutational mechanisms underpinning signatures caused by replication errors and endogenous DNA damage

Xueqing Zou, Ching Chiek Koh, Arjun Scott Nanda…·Magdalena Zarowiecki

The paper identifies gene-specific mutational signatures caused by replication errors and endogenous DNA damage using CRISPR-Cas9 knockouts and whole-genome sequencing.

160 citationstop 1%

humanwhole-genome sequencing

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GenomicseLifePeer-reviewedAug 10, 2020

Population-scale proteome variation in human induced pluripotent stem cells

Bogdan Andrei Mirauta, Daniel D. Seaton, Dalila Bensaddek…·Philip L. Beales

The paper characterizes proteome variation across 202 human iPSC lines, identifies 700 pQTLs, and links pQTLs to disease-associated GWAS variants.

59 citationstop 3%

humanproteomics

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GenomicsNature CommunicationsPeer-reviewedFeb 10, 2020

Single-cell RNA-seq of differentiating iPS cells reveals dynamic genetic effects on gene expression

Anna S. E. Cuomo, Daniel D. Seaton, Davis James McCarthy…·Oliver Stegle

The paper uses single-cell RNA-seq of differentiating iPS cells from 125 donors to identify expression quantitative trait loci influencing gene expression during endoderm differentiation.

331 citationstop 1%

humanscRNA-seq

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