The type I and III interferon responses restrict infection with tick-borne orthoflaviviruses through IFI6
Félix Streicher, Devin Kenney, Vincent Caval, Maxime Chazal, Sophie‐Marie Aicher, Ségolène Gracias, Scott Adams, Mao Matsuo, Ferdinand Roesch, Florian Douam, Nolwenn Jouvenet
This study identifies IFI6 as a key antiviral effector mediating type I and III interferon restriction of tick-borne orthoflaviviruses in human cells and mice.
Journal of Virology · Apr 14, 2026Peer-reviewedMicrobiology