Context-Dependent and Gene-Specific Role of Chromatin Architecture Mediated by Histone Modifiers and Loop-extrusion Machinery
Melodi Tastemel, Adam Jussila, Bharath Saravanan…·Bing Ren
The paper investigates how chromatin architecture, mediated by histone modifiers and loop-extrusion machinery, influences gene regulation in mouse embryonic stem cells under different conditions.