Author

Xiaobin Wu

Guangzhou Women and Children Medical CenterORCID 0000-0002-8382-6005Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biochemistry· 1

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Research Focus:metabolism & bioenergetics· 1 Assay:metabolomics· 1

Frequent Co-Authors

Jintian WangiD· 1 shared Junfeng Zheng· 1 shared Miao ZhouiD· 1 shared Qian CheniD· 1 shared Xuan ZhangiD· 1 shared Xudong Jiang· 1 shared Youhao Yang· 1 shared

Activity by Year

2024-2024 · peak 1/yr

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7 top collaborators · 21 mutual co-author links

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1 shared paperBiochemistry

Jintian WangORCID

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1 paper

Recent·Most cited

BiochemistrybioRxivPreprintAug 9, 2024

Pyruvate kinase allostery resist hyperglycemia, obesity and inflammation by inducing TCA vortex and glucose U turn

Xuan Zhang, Xudong Jiang, Xiaobin Wu…·Qian Chen

This study shows that CLT-PKM interaction mimics ATP resistance by inducing a TCA vortex and glucose U turn, leading to weight loss and antioxidant effects against hyperglycemia, obesity, and inflammation.

DOI 10.1101/2024.08.09.607407

metabolomicsexperimental assay