Qian Chen

This study shows lactic acid promotes intervertebral disc degeneration by causing stem cell senescence and DNA damage through oxidative stress and cell cycle arrest.

This study shows that CLT-PKM interaction mimics ATP resistance by inducing a TCA vortex and glucose U turn, leading to weight loss and antioxidant effects against hyperglycemia, obesity, and inflammation.

The paper characterizes head direction (HD) cells in the somatosensory cortex, finding that fast-spiking inhibitory neurons are sharply tuned to HD and have distinct organizational features.