MicrobiologybioRxivPreprint
Regulation of virion production by the ORF8 signal peptide across SARS-CoV-2 variants
Mir Mubashir Khalid, Irene P. Chen, Frank W. Soveg…·Mélanie Ott
This study shows ORF8 suppresses viral particle production by interacting with Spike and causing Golgi fragmentation, supporting evolutionary pressure to delete ORF8 in SARS-CoV-2 variants.
12 citations