Tomoshi Tsuchiya

This study characterizes epithelial cell states emerging from reprogramming in a pulmonary bioengineering context.

This paper introduces a tunable lung organoid model to study how cellular composition drives epithelial plasticity and immune polarization in chronic lung diseases.

This study develops an engineered whole-lung tissue model to study tissue organization and alveolar barrier function, showing improved barrier function with alveolar macrophages.

This study compares the patho-transcriptomic profiles of invasive mucinous adenocarcinoma (IMA) and adenocarcinoma with signet ring cell features (SRCC), identifying distinct and shared gene expression patterns and potential therapeutic targets.

The paper identifies cell-to-cell communication between mesothelial cells and alveolar tuft cells that regulates lung regeneration after pneumonectomy.