Author

Satoshi Mizoguchi

Yale UniversityORCID 0000-0002-6099-1702Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioengineering· 3 Systems Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Research Focus:cell type annotation· 3 Research Focus:cell-cell communication· 2 Research Focus:development & morphogenesis· 2 Assay:organoid / primary culture· 2 Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1 Organism:mouse· 1

Frequent Co-Authors

Micha Sam Brickman RaredoniD· 4 shared Sophie E. EdelsteiniD· 4 shared Tomoshi TsuchiyaiD· 4 shared Allison Marie GreaneyiD· 3 shared N.-K. WangiD· 3 shared Naftali KaminskiiD· 3 shared Tomohiro ObataiD· 3 shared Colten Danelski· 2 shared

Activity by Year

2024-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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4 shared papersBioengineering

Micha Sam Brickman RaredonORCID

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4 papers

Recent·Most cited

Epithelial Reprogramming and Transition during Pulmonary Bioengineering

Satoshi Mizoguchi, VI Lee, Hahram Kim, Sophie E. Edelstein, Nuoya Wang, Maria Tomàs Gracia, Colten Danelski, Connor V Haynes, Rachel Rivero, David H. Stitelman, Tomohiro Obata, Allison Marie Greaney, Tomoshi Tsuchiya, Themis R. Kyriakides, Naftali Kaminski, Micha Sam Brickman Raredon

This study characterizes epithelial cell states emerging from reprogramming in a pulmonary bioengineering context.

bioRxiv · Jan 26, 2026 · PreprintBioengineering

A Tunable Pulmonary Organoid Model Demonstrates Compositionally Driven Epithelial Plasticity and Immune Polarization

Sophie E. Edelstein, Satoshi Mizoguchi, Maria Tomàs Gracia, N.-K. Wang, V. W. S. Lee, Hahram Kim, Connor V Haynes, Colten Danelski, Tomoshi Tsuchiya, Maor Sauler, Micha Sam Brickman Raredon

This paper introduces a tunable lung organoid model to study how cellular composition drives epithelial plasticity and immune polarization in chronic lung diseases.

bioRxiv · Jun 5, 2025 · PreprintBioengineering

Engineered Whole Lungs for Tissue Biology

Allison Marie Greaney, Micha Sam Brickman Raredon, Tomohiro Obata, Juan Wang, Taylor Sterling Adams, Jonas C. Schupp, Satoshi Mizoguchi, Sophie E. Edelstein, Yifan Yuan, Pavlina Baevova, N.-K. Wang, Alexander J. Engler, Katherine L. Leiby, Tomoshi Tsuchiya, Robert Homer, , Ruslan M. Medzhitov

This study develops an engineered whole-lung tissue model to study tissue organization and alveolar barrier function, showing improved barrier function with alveolar macrophages.

bioRxiv · Oct 2, 2024 · PreprintBioengineering

Organ Boundary Circuits Regulate Sox9+ Alveolar Tuft Cells During Post-Pneumonectomy Lung Regeneration

Tomohiro Obata, Satoshi Mizoguchi, Allison Marie Greaney, Taylor Sterling Adams, Yifan Yuan, Sophie E. Edelstein, Katherine L. Leiby, Rachel Rivero, N.-K. Wang, Haram Kim, Junchen Yang, Jonas C. Schupp, David H. Stitelman, Tomoshi Tsuchiya, Andre Levchenko, , Micha Sam Brickman Raredon

The paper identifies cell-to-cell communication between mesothelial cells and alveolar tuft cells that regulates lung regeneration after pneumonectomy.

bioRxiv · Jan 7, 2024 · PreprintSystems Biology